ABSTRACT
Sixty three cases of clinically and radiologically diagnosed osteosarcomas were evaluated by fine needle aspiration cytology over a five year period. Adequate material was obtained in 59 cases. The sites aspirated were femur, tibia, humerus, fibula, scapula and clavicle. The mean age was 16 years. The most frequent morphological type encountered was the pleomorphic tumor (42) the other cytological types were sclerotic (10), chondroid (6), and small cell osteosarcoma (1). Hematoxylin and Eosin stain was better suited for detection of osteoid than routinely done cytological stain. The awareness of this cytological diversity is essential to avoid misinterpretation of osteosarcomas.
Subject(s)
Adolescent , Adult , Biopsy, Needle , Bone Neoplasms/pathology , Cell Nucleus/pathology , Child , Female , Humans , Male , Osteosarcoma/pathologyABSTRACT
Two hundred and forty osteolytic lesions were biopsied by means of a fine needle. The procedure yielded adequate material in 92 percent of the cases. A definitive diagnosis with correct cell typing was provided in 89 per cent of the adequate samples. Processing of the aspirated clot in addition, in 142 cases, provided fragments of tumour tissue in its histological milieu, a feature lost in cytologic smears. FNAC can be effectively used in the screening of various musculo-skeletal mass lesions and their management.